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Harvard Case - Jake Becraft and Strand Therapeutics: The Making of an Entrepreneur

"Jake Becraft and Strand Therapeutics: The Making of an Entrepreneur" Harvard business case study is written by Satish Tadikonda, William Marks, Ananya Zutshi. It deals with the challenges in the field of Entrepreneurship. The case study is 15 page(s) long and it was first published on : Aug 14, 2023

At Fern Fort University, we recommend that Jake Becraft continue to pursue his entrepreneurial vision for Strand Therapeutics, focusing on strategic partnerships, targeted fundraising, and a lean, agile approach to product development and market validation. This will enable Strand Therapeutics to navigate the complexities of the biotech industry, secure necessary resources, and establish a strong foundation for future growth and potential exit strategies.

2. Background

Jake Becraft, a young and ambitious entrepreneur, founded Strand Therapeutics with the goal of revolutionizing the treatment of genetic diseases. Driven by a personal connection to the challenges of genetic disorders, Becraft developed a novel technology platform based on CRISPR-Cas9 gene editing. The company faced the typical challenges of a biotech startup, including securing funding, building a team, and navigating the complex regulatory landscape.

The case study focuses on Becraft?s journey as he navigates the early stages of his entrepreneurial venture. Key protagonists include Jake Becraft himself, the founder and CEO, as well as his team of scientists, advisors, and potential investors.

3. Analysis of the Case Study

The case study presents a compelling example of the challenges and opportunities faced by entrepreneurs in the biotech sector. To analyze the situation, we can apply the following frameworks:

a) Business Model Canvas: This framework helps to understand the key elements of Strand Therapeutics? business model, including:* Value Propositions: Strand Therapeutics offers a novel gene editing technology with the potential to cure genetic diseases.* Customer Segments: Their target market includes patients with genetic disorders, healthcare providers, and pharmaceutical companies.* Channels: They can reach their customers through scientific publications, conferences, and collaborations with research institutions.* Customer Relationships: Building trust and credibility with potential partners and investors is crucial.* Revenue Streams: Potential revenue streams include licensing fees, royalties, and partnerships with pharmaceutical companies for drug development.* Key Resources: Strand Therapeutics relies on its scientific expertise, intellectual property, and access to funding.* Key Activities: Research and development, clinical trials, and business development are essential activities.* Key Partnerships: Collaborations with research institutions, universities, and investors are critical.* Cost Structure: The company faces significant costs associated with research, development, clinical trials, and regulatory approvals.

b) SWOT Analysis: This framework helps to identify Strand Therapeutics? strengths, weaknesses, opportunities, and threats:* Strengths: Strong scientific team, innovative technology platform, potential for significant impact on patient lives.* Weaknesses: Limited resources, early stage of development, high regulatory hurdles.* Opportunities: Growing market for gene editing therapies, potential for partnerships with pharmaceutical companies, access to venture capital funding.* Threats: Competition from established players, regulatory uncertainty, potential for ethical concerns.

c) Entrepreneurial Finance: This framework helps to understand the financial challenges and opportunities faced by Strand Therapeutics:* Funding Sources: Becraft needs to secure funding through a combination of bootstrapping, angel investing, venture capital, and potential government grants.* Valuation: The company?s valuation will depend on the stage of development, technology, and potential market size.* Financial Projections: Developing accurate financial projections is crucial for attracting investors and securing funding.

4. Recommendations

a) Strategic Partnerships: Strand Therapeutics should actively seek strategic partnerships with pharmaceutical companies, research institutions, and other biotech startups. These partnerships can provide access to resources, expertise, and market reach.

b) Targeted Fundraising: Becraft should focus on securing funding from venture capital firms specializing in biotechnology and healthcare. He should develop a compelling pitch that highlights the technology?s potential, the market opportunity, and the company?s strong team.

c) Lean, Agile Approach: The company should adopt a lean startup methodology, focusing on rapid prototyping, customer discovery, and minimum viable product (MVP) development. This will allow them to validate their technology and business model quickly and adapt based on market feedback.

d) Product Development and Market Validation: Strand Therapeutics should prioritize product development and market validation. This involves conducting rigorous clinical trials, obtaining regulatory approvals, and building a strong intellectual property portfolio.

e) Building a Strong Team: Becraft should continue to build a strong and diverse team with expertise in science, business development, finance, and regulatory affairs.

5. Basis of Recommendations

These recommendations are based on the following considerations:

1. Core Competencies and Consistency with Mission: Strand Therapeutics? core competency lies in its innovative gene editing technology. The recommendations align with the company?s mission to develop life-changing therapies for genetic diseases.

2. External Customers and Internal Clients: The recommendations consider the needs of external customers (patients, healthcare providers, pharmaceutical companies) and internal clients (employees, investors).

3. Competitors: The recommendations acknowledge the competitive landscape and emphasize the need for strategic partnerships and rapid product development.

4. Attractiveness ? Quantitative Measures: The recommendations aim to increase the company?s attractiveness to investors by demonstrating strong scientific progress, a clear market opportunity, and a well-defined business model.

5. Assumptions: The recommendations are based on the assumption that Strand Therapeutics? technology is viable, the market for gene editing therapies is growing, and the company can secure necessary funding.

6. Conclusion

Strand Therapeutics has the potential to make a significant impact on the treatment of genetic diseases. By focusing on strategic partnerships, targeted fundraising, and a lean, agile approach to product development and market validation, Jake Becraft can navigate the challenges of the biotech industry and establish a strong foundation for future growth and success.

7. Discussion

Alternatives:

  • Going public: While going public could provide access to significant capital, it is not recommended at this early stage due to the company?s limited track record and high regulatory hurdles.
  • Acquisition by a larger company: This could provide access to resources and expertise, but it would require a significant valuation and potentially limit Becraft?s control over the company.

Risks:

  • Technology failure: If the technology does not perform as expected, the company could face significant setbacks.
  • Regulatory hurdles: Obtaining regulatory approvals for gene editing therapies can be challenging and time-consuming.
  • Competition: The gene editing market is becoming increasingly competitive, with established players and new startups entering the field.

Key Assumptions:

  • The technology is viable and effective.
  • The market for gene editing therapies will continue to grow.
  • The company can secure necessary funding.

8. Next Steps

  • Develop a detailed business plan: This should include financial projections, a market analysis, and a clear roadmap for product development and commercialization.
  • Secure seed funding: Becraft should focus on securing seed funding from angel investors and venture capital firms specializing in biotechnology.
  • Build a strong team: The company should recruit talented scientists, business development professionals, and regulatory experts.
  • Develop a minimum viable product (MVP): This will allow the company to test its technology and business model in the market.
  • Seek strategic partnerships: Becraft should actively seek partnerships with pharmaceutical companies, research institutions, and other biotech startups.

By following these steps, Strand Therapeutics can increase its chances of success in the competitive biotech industry and make a positive impact on the lives of patients with genetic disorders.

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Case Description

Jake Becraft, a PhD student at MIT disillusioned in pursuit of his dreams of becoming an academic, serendipitously finds himself discussing the potential commercial applications of his work with Tasuku Kitada, his former postdoctoral research mentor. The two decide to alter the course of both of their lives, join forces, and begin down an entrepreneurial road to found Strand Therapeutics. The journey features the genesis of Becraft's ideas, the pursuit of those ideas, the path to entrepreneurship and the associated challenges, including many bumps, twists and turns along the way.

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